Diagnostic and Prognostic Role of Pleural Fluid Neutrophil-to Lymphocyte and Monocyte-to-Lymphocyte Ratios in Exudative Pleural Effusion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- MLR and NLR measuring in pleural fluid
研究概览
简要总结
Exudative pleural effusion (EPE) presents a diagnostic challenge, requiring accurate biomarkers to predict outcomes and guide treatment. The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) in pleural fluid are emerging as potential prognostic markers. We aimed to assess the diagnostic and prognostic utility of pleural fluid NLR and MLR in EPE.
详细描述
Pleural fluid NLR and MLR are reliable biomarkers for diagnosing malignant pleural effusion and predicting poorer survival outcomes. These ratios may be useful in clinical practice, especially in resource-limited settings, to guide decision-making in the management of pleural effusions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Months 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients aged 18-80 years with an EPE diagnosis confirmed by thoracentesis.
排除标准
- •Exclusion criteria included patients with a history of recent surgery, corticosteroid use, or those with mixed effusion types.
结局指标
主要结局
MLR and NLR measuring in pleural fluid
时间窗: 1 month
counting pleural fluid monocytes,lymphocytes and neutrophils
次要结局
未报告次要终点
研究者
Mohamed Sabry
Lecturer of chest diseases
Alexandria University