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临床试验/TCTR20220705002
TCTR20220705002Unknown4 期

Pain control effectiveness of curcumin compare with ibuprofen after lower third molar removal surgery and A double blind randomized clinical trial

Ministry of Higher Education, Science, Research and Innovation, Prince of Sonkla University0 个研究点目标入组 76 人开始时间: 2022年7月5日最近更新:
适应症

试验速览

阶段
4 期
发起方
入组人数
76

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 Years 至 29 Years(—)
性别
All

入选标准

  • 1. Patients aged between 18 to 29 years
  • 2. Weight 40-90 kgs
  • 3. Clear indication for removal of lower third molars
  • 3. Health patients with no uncontrolled systemic disease that is unsuitable to lower the third molar impacted
  • 4. The moderate difficulty of lower third molar (Pederson difficulty index 5-6 score)
  • 5. Operation time must be less or equal to 1 hour
  • 6. An absence of periodontal disease, infection, swelling before surgery
  • 7. Same person to surgery second time greater than or equal to 3 weeks

排除标准

  • 1. Taking analgesic medications, such as aspirin, paracetamol, NSAIDs, opioids, or any other agents between 24 hours and 2 weeks before surgery
  • 2. Patients with a history of severe asthma, gastrointestinal disorders such as Dyspepsia or Peptic ulcer(PU)) Bile duct obstruction, hematologic, renal, or hepatic disease; immunosuppressive disorder; neurological disorder affecting pain perception
  • 3. Taking medication (use anticoagulant or antiplatelet, cancer drugs)
  • 4. Pregnancy and Lactation
  • Allergy to Local anesthetic, NSAID(Ibuprofen), curcumin, amoxicillin, tramadol, and paracetamol
  • 5. Smoking

研究者

发起方
Ministry of Higher Education, Science, Research and Innovation, Prince of Sonkla University

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