NCT02804100Unknown不适用
A Multi-centre Observational Study on Dynamic Changes of Circulating Tumor DNA in Late Stage NSCLC Patients Under Gefitinib Treatment
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- dynamic changes of circulating tumor DNA in late stage NSCLC patients under Gefitinib treatment
研究概览
简要总结
A multi-centre observational, non-interventional study is to dynamically monitor the changes of circulating tumor DNA (ctDNA) in late stage NSCLC patients under Gefitinib treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Provision of informed consent
- •Histologically confirmed stage IIIB/IV NSCLC.
- •Activating EGFR mutations (G719A/C/S; Exon 19 insertion/deletion; L858R; L861Q)
- •Able to comply with the required protocol and followed-up procedures, and able to receive oral medications
排除标准
- •Histologically confirmed small cell lung cancer or other metastatic tumors
- •Patient had received prior chemotherapy or EGFR-TKIs treatment
- •Patients who harbor Exon20 T790M mutation
结局指标
主要结局
dynamic changes of circulating tumor DNA in late stage NSCLC patients under Gefitinib treatment
时间窗: 2 years
次要结局
未报告次要终点
研究者
Chunming Ding
Professor
Wenzhou Medical University
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Multicenter prospective observational study on the effectiveness of hypofractionated palliative radiotherapy for advanced head and neck squamous cell carcinoma (JROSG 18-2)Advanced head and neck squamous cell carcinomaJPRN-UMIN000039971Japanese Radiation Oncology Study Group (JROSG)50
已完成
不适用
An observational study focusing on the changes of the upper eyelid sulcus after switching from FP receptor agonist to omidenepag isoproryl ophthalmic solutioGlaucoma, ocular hypertensionJPRN-UMIN000036705Yotsuya Shirato Eye Clinic23
招募中
不适用
Evaluation of Enavogliflozin's Efficacy and Safety in Type II Diabetes With Hypertension or DyslipidemiaDiabetes Mellitus, Type 2NCT06647888Daewoong Pharmaceutical Co. LTD.12,000
进行中（未招募）
不适用
Noninterventional Study Evaluating Parkinson's Disease Diary UseParkinson's DiseaseNCT05363046BlueRock Therapeutics194
Unknown
不适用
COMMUNITY STUDY- A Study to Collect Information for the Cordio SystemHeart FailureNCT03438799Cordio Medical500