Impact of Number of Rank of B-lactam Antibiotics on Emergence on Multidrug Resistant Bacteria
试验速览
- 阶段
- 不适用
- 入组人数
- 1,300
- 主要终点
- number of Beta lactam class prescription
研究概览
简要总结
This study evaluates the impact of rank of Beta lactam antibiotics on emergence of mutlidrug resistant bacteria colonization in intensive care
It's retrospective case controle study. Cases are colonized patient by multidrug resistant bacteria hospitalized in intensive care during the fist hospitalization in intensive care. Temoin are patients with the same characteristics than case but no colonized by multidrug resistant bacteria.
详细描述
The emergence of multidrug resistant is a wordwide problem. B lactam resistant increase. The antibiotic prescription impact this problem.
B lactam antibiotic is prescribed everyday in intensive care unit. The switch of antibiotic is common. Antibiotic classes inclue a lot of rank with different spectum that impact the occurrence of resistant.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •all patient hospitalized more than 48 hours in intensive care unit in Besançon between january 2016 and december 2017
排除标准
- •patient under guardianship
- •patient allergic to Beta lactam
- •colonization with mutidrug resistant the first week of hospitalization in intensive care unit
结局指标
主要结局
number of Beta lactam class prescription
时间窗: 3 months
次要结局
未报告次要终点
研究者
Estelle Dossot
Internal
Centre Hospitalier Universitaire de Besancon