TCTR20210525007尚未招募4 期
Effect of MK-7 supplementation to dp-ucMGP levels in chronic hemodialysis patients receiving phosphate binders
The College of Pharmacotherapy of Thailand0 个研究点目标入组 30 人开始时间: 2021年5月25日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 N/A (No limit)（—）
- 性别
- All
入选标准
- •1.Thai adults chronic hemodialysis patients
- •2.Receiving monotherapy of phosphate binder
排除标准
- •1.History of cardiovascular diseases
- •2.History of coagulation defects
- •3.History of malignancy
- •4.Presence of lipid absorption disorders
- •5.Elevated liver enzymes, above 3 times the upper limit of normal
- •6.Serum albumin less than 2.5 g/dL
- •7.Body mass index less than 18 kg/m2
- •8.VitaminK antagonists treatment within 90 days prior to recruitment
- •9.Concomitant drugs affect vitaminK levels e.g. carbamazepine, cholestyraine, lamotrigine, menadione, menaquinone, orlistat, oxcarbamazepine, phenobarbital, phenytoin, phytomenadione
- •10.Receiving antibiotics at least 10 days during recruitment
- •11.Phosphate binders dose adjustment within 30 days prior to recruitment
- •12.Hypersensitivity to menaquinone or any component of the formulation
- •13.Medication adherence less than 80%
- •14.Refuse to participate
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