Effects of Probiotic With HIIT on Cardiorespiratory Endurance and Metabolism in Middle-Aged Obese Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 1
- 主要终点
- Total cholesterol (TC)
研究概览
简要总结
The aim of this study is to investigate whether there are the additive effects when implementing both high-intensity interval training (HIIT) and probiotics simultaneously on improving cardiorespiratory endurance and metabolism in middle-aged women.
详细描述
High-intensity interval training (HIIT) is a time-efficiency exercise mode that has been shown to reduce body fat, fasting blood insulin levels, arterial stiffness, and aerobic capacity, helping to prevent and improve chronic diseases. Probiotics, on the other hand, have been found to have similar effects, including improving insulin sensitivity and endurance exercise performance, as well as reducing body fat. However, the additive effects of HIIT combined with probiotic supplements are unclear. In addition, on average, the life expectancy of women is longer than that of men. Middle-aged women are at high-risk for obesity and metabolic-related problems that threaten their long-term health. Therefore, whether the combination of HIIT and probiotics can be utilized to enhance the wellness of middle-aged women is the objective of this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 35 Years 至 55 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age between 35-55 years old
- •Total body fat percentage greater than 30%
排除标准
- •Participants who were taking probiotics supplementation or antibiotics
- •Percentage of total body fat less than 30%
研究组 & 干预措施
Placebo control (C)
The subjects do not perform HIIT training, but consume one placebo packet every day on a fasting status for 8 weeks.
干预措施: Placebo supplementation (Dietary Supplement)
Probiotics supplementation (P)
Each participant consume one probiotic packet every day on a fasting status for 8 weeks.
干预措施: Probiotics supplementation (Dietary Supplement)
HIIT intervention (H)
HIIT training for 3 sessions per week and consume one placebo packet every day on a fasting status for 8 weeks.
干预措施: HIIT training (Behavioral)
HIIT intervention (H)
HIIT training for 3 sessions per week and consume one placebo packet every day on a fasting status for 8 weeks.
干预措施: Placebo supplementation (Dietary Supplement)
HIIT with probiotics intervention (HP)
Conduct HIIT training 3 sessions per week for 8 weeks and consume one probiotic packet every day on a fasting status for 8 weeks.
干预措施: Probiotics supplementation (Dietary Supplement)
HIIT with probiotics intervention (HP)
Conduct HIIT training 3 sessions per week for 8 weeks and consume one probiotic packet every day on a fasting status for 8 weeks.
干预措施: HIIT training (Behavioral)
结局指标
主要结局
Total cholesterol (TC)
时间窗: 8 weeks
TC in mg/dL
Body weight
时间窗: 8 weeks
Weight in kilograms
Waist circumference
时间窗: 8 weeks
Waist circumference in centimeters
Fasting blood glucose (FBG)
时间窗: 8 weeks
FBG in mg/dL
Body fat percentage
时间窗: 8 weeks
Body fat percentage (%) is measured with Dual-energy X-ray absorptiometry (DEXA)
Hip circumference
时间窗: 8 weeks
Hip circumference in centimeters
Maximum oxygen uptake (VO2max)
时间窗: 8 weeks
VO2max in ml/min/kg
Time to exhaustion (TTE)
时间窗: 8 weeks
TTE in seconds
Running economy (RE)
时间窗: 8 weeks
RE in ml/kg/km
Triglyceride (TG)
时间窗: 8 weeks
TG in mg/dL
High-density lipoprotein cholesterol (HDL-C)
时间窗: 8 weeks
HDL-C in mg/dL
Low-density lipoprotein cholesterol (LDL-C)
时间窗: 8 weeks
LDL-C in mg/dL
Height
时间窗: 8 weeks
Height in centimeters
Body mass index (BMI)
时间窗: 8 weeks
Calculated by: weight (kg)/ height (m\^2)
次要结局
- Muscle mass(8 weeks)
- Fat mass(8 weeks)
- Bone mineral density (BMD)(8 weeks)
- Caloric intake(8 weeks)
研究者
Chien-Wen Hou
Principle investigator
University of Taipei