Evaluation of Collagen Versus Platelet Rich Fibrin Membrane on the Osteogenic Potential of Bone Marrow Aspirate Concentrate (BMAC) for Lateral Sinus Floor Augmentation : A Randomized Clinical Trial.
试验速览
- 阶段
- 不适用
- 入组人数
- 2
- 试验地点
- 1
- 主要终点
- Radiographic Bone density assessment
研究概览
简要总结
Utilization of collagen vs PRF membrane over the graft following sinus lift procedure and before suturing
详细描述
Assessment of the effect of membrane overlying bone marrow aspirate concentrate - bovine graft mixture in sinus lift procedure
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients who has as deficient as 4 mm vertical bone height in posterior maxilla that need bone augmentation before delayed implant placement.
- •Highly motivated patients
- •Age more than 18 years
排除标准
- •Patients suffering from any systemic disease or those under any medication that may interfere with normal bone healing.
- •Patients suffering from any sinus pathosis.
- •Patients with conditions that could potentially compromise Bone Marrow ( BM)quality, including history of hematologic malignancy, current chemotherapy, BM suppressive and anti-platelet medications, previous BM Aspiration, or acute illness.
- •Heavy smoker (> 20 cigarettes daily)
研究组 & 干预措施
Collagen membrane covering BMAC loaded on bovine graft
Collagen membrane will be used to BMAC loaded on bovine graft . Variables include assessment of the osteogenic potential In terms of bone density measurements of graft immediate and 4 months Postoperative
干预措施: Collagen membrane over BMAC/bovine graft in sinus lift (Procedure)
PRF membrane covering BMAC loaded on bovine graft
Platelet rich fibrin membrane will be used to BMAC loaded on bovine graft . Variables include assessment of the osteogenic potential In terms of bone density measurements of graft immediate and 4 months Postoperative
干预措施: PRF membrane over BMAC/bovine graft in sinus lift (Procedure)
结局指标
主要结局
Radiographic Bone density assessment
时间窗: 4 months ( immediate - 4 months postoperative)
Bone density measurements on Cone beam CT/CBCT immediate and 4 months radiographic density measurements in haunsfield units, immediate and 4 months postoperative
次要结局
- Radiographic Bone height assessment(4 months ( immediate - 4 months postoperative))
研究者
Walaa Kadry
Lecturer of oral and Maxillofacial Surgery
Cairo University