Impact of Blueberries on Uric Acid and Quality of Life
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Change from Baseline and Placebo in Uric Acid Level in Patients Randomized to Treatment Group
研究概览
简要总结
The purpose of this study is to determine the impact of blueberries on uric acid in patients with hyperuricemia that are not receiving uric acid pharmacotherapy. The central hypothesis the investigators propose is that daily blueberries added to a pre-existing diet will promote uric acid lowering and improve quality of life without detriment to vital signs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 88 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years or older
- •Uric acid > 6.0 mg/dL
排除标准
- •Current moderate-to-severe symptomatic gout
- •Currently receiving gout pharmacotherapy
- •Current participation in another clinical trial
- •Documented non-compliance or consistent missed appointments
- •Women who are pregnant or nursing
结局指标
主要结局
Change from Baseline and Placebo in Uric Acid Level in Patients Randomized to Treatment Group
时间窗: Baseline, ~30 days later
Percent change in uric acid level from baseline after 30 days of treatment with blueberry powder. Since this is designed as a crossover trial, baseline could represent uric acid level at the beginning of the study or after at least a 2-week washout period following placebo administration.
次要结局
- Body Weight(Baseline, ~30 days, ~45 days, ~75 days)
- Blood Pressure(Baseline, ~30 days, ~45 days, ~75 days)
- Quality of Life(Baseline, ~30 days, ~45 days, ~75 days)
研究者
Daniel Riche
Associate Professor
University of Mississippi Medical Center