Efficacy of Ozone Gel, Doxycycline Saturated Chitosan Dressing Versus Alveogyl in Pain Alleviation and Healing of Alveolar Osteitis in Diabetic Patients Double Blind Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Pain scores will be recorded on visual analog scale (VAS)
研究概览
简要总结
Efficacy of ozone gel, doxycycline saturated chitosan dressing versus Alveogyl in pain alleviation and healing of alveolar osteitis in diabetic patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients over 20 years and under 60 years of age
- •DM controlled by medication, presented to outpatient clinic with signs and symptoms of dry socket
- •Only participant that are willing to control and record blood glucose level throughout the study period
排除标准
- •Patients with any significant medical condition (besides DM)
- •Alcoholic individuals
- •Patients on drugs that affect the central nervous systems
- •Patients who reported the use of drugs that might interfere with pain sensitivity
- •Pregnant and lactating women
- •Hypersensitivity to local anesthetics
研究组 & 干预措施
Ozone gel
(Ozene; Premier Research Labs, lp, 3500-b Wadley pl, Austin, TX, USA. 78728)
干预措施: Ozone gel (Drug)
doxycycline hyclate saturated chitosan dressing
doxycycline hyclate ( Atridox 10% Tolmar Inc, USA) saturated chitosan dressing (HHD) HemCon dental dressing Pro ( Tricol Biomedical, Inc. USA)
干预措施: doxycycline hyclate saturated chitosan dressing (Drug)
Alveogyl paste
Alveogyl paste ( Septodont, inc, france)
干预措施: Ozone gel (Drug)
Alveogyl paste
Alveogyl paste ( Septodont, inc, france)
干预措施: doxycycline hyclate saturated chitosan dressing (Drug)
结局指标
主要结局
Pain scores will be recorded on visual analog scale (VAS)
时间窗: 7 days
visual analog scale (VAS) is a scale from 0 to 10. 0 indicates no pain while indicates extensive unbearable pain
次要结局
- Healing score of the extraction socket(21 days)
研究者
Tarek Abdelbarry
Lecturer of Oral and Maxillofacial Surgery
Minia University