NCT06607653尚未招募不适用
The Efficacy of Olfactory Training Intervention on Olfactory and Other Non-motor Symptoms in PD
未提供1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年9月25日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Olfactory Function Test
研究概览
简要总结
To explore the efficacy of olfactory training on olfactory and other non-motor symptoms in PD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •PD was diagnosed according to the criteria of Movement Disorders and Parkinson Disease Group of Chinese Society of Neurology of Chinese Medical Association.
- •Olfactory score was 1 standard deviation lower than the corresponding age norm;
- •no medication plan in the past four weeks or no change in medication plan in the past four weeks, which can be maintained until the end of the experiment; 4.40-75 years old, with normal vision, hearing and language understanding and expression ability;
- •5.Good cooperation of patients
排除标准
- •Parkinson's syndrome and Parkinson's plus syndrome caused by cerebrovascular disease, encephalitis, trauma, drugs, etc.;
- •Neuropsychiatric diseases that may affect the sense of smell, such as depression, anxiety, schizophrenia, etc.;
- •History of nasal disease or surgery, such as rhinitis, sinusitis, nasal septum deviation, etc. Upper respiratory tract infection in the past 3 weeks;
- •Long-term smoking and occupations that inhale chemical irritants for a long time.
结局指标
主要结局
Olfactory Function Test
时间窗: baseline;15 weeks
The olfactory test developed by the Institute of Psychology, Chinese Academy of Sciences was used to evaluate the olfactory ability, including threshold, discrimination, and recognition.
次要结局
- MoCA(baseline;15 weeks)
- Pittsburgh sleep quality index(baseline;15 week)
- HAMA(baseline;15week)
- HAMD(baseline;15 week)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
3 期
Effect of olfactory training on olfactory disorders caused by covid-19 diseaseIRCT20221023056273N1Kashan University of Medical Sciences66
招募中
不适用
Olfactory Training on Smell Dysfunction Patients in HKOlfaction DisordersSmell DisordersHyposmiaOlfactory ImpairmentSmell LossSmell DysfunctionAnosmiaNCT05364125Pamela Youde Nethersole Eastern Hospital80
尚未招募
不适用
Effect of training with odors on olfactory and nociceptive function in childreG43.0G43.1Migraine without aura [common migraine]Migraine with aura [classical migraine]DRKS00021062TU DresdenUniversitätsklinikum200
招募中
不适用
The effect of training on the improvement of olfactory disorder and sexual satisfaction in patients with anosmia/hyposmiaPost traumatic Anosmia/Hyposmia.Sequelae of injuries, of poisoning and of other consequences of external causesT90-T98IRCT2017102034225N1Research Center of the ear, throat, nose and head and neck of Iran120
尚未招募
2 期
Effect of olfactory training on anosmia of COVID-19oss of smell, Olfactory Rehabilitation.R43.0AnosmiaIRCT20200629047953N1Tehran University of Medical Sciences40