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临床试验/NCT04815525
NCT04815525招募中不适用

The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong

Chinese University of Hong Kong1 个研究点 分布在 1 个国家目标入组 5,000 人开始时间: 2023年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
5,000
试验地点
1
主要终点
Culumative incidence of advanced colorectal neoplasia

研究概览

简要总结

The primary objective of this study is to analyze the 15-year cumulative incidence of advanced colorectal neoplasia and CRC-related mortality after the index colonoscopy.

详细描述

This is a territory-wide retrospective observational cohort study using the Clinical Data Analysis and Reporting System (CDARS). We will identify patients from CDARS with colonoscopy performed from 1 January 2000 to 31 October 2020. Other relevant diagnoses, procedures, concomitant drugs, laboratory parameters and pathology results will be retrieved and studied.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • All patients with colonoscopy performed in HA hospitals during the study period would be eligible for screening.

排除标准

  • Patients with documented personal history of colorectal cancers before the study period would be excluded.

结局指标

主要结局

Culumative incidence of advanced colorectal neoplasia

时间窗: 15 years

high-risk adenomas or CRC after 15 years of index conoloscopy

次要结局

  • CRC-related mortality rate(15 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Louis Ho Shing Lau

Resident Specialist

Chinese University of Hong Kong

研究点 (1)

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