Ultrasound Guided Erector Spinae Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Cholecystectomy Surgeries: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 主要终点
- The degree of postoperative pain in the first 24 hours post-operative
研究概览
简要总结
The aim of this study is to compare between the efficacy of ultrasound guided erector spinae plane block and ultrasound guided quadratus lumborum block in managing acute postoperative pain in patients undergoing laparoscopic cholecystectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
Patients and medical personnel collecting data and conducting follow-up will be blinded to the group of the patient. All blocks will be performed by one anesthesiologist who will not participate in data collection or analysis.
入排标准
- 年龄范围
- 21 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged 21-65 years
- •both genders
- •American Society of Anesthesiology (ASA) class I-II
- •Undergoing elective laparoscopic cholecystectomy
排除标准
- •Patient refusal.
- •Coagulopathy.
- •History of allergy to local anaesthetic.
- •History of liver or renal pathology affecting drug elimination
- •Mental dysfunction or cognitive disorders.
- •Use of medication such as gabapentin-pregabalin that could affect pain perception.
- •Body Mass Index > 40 kg/m2.
研究组 & 干预措施
Control group
patients will receive general anesthesia only.
干预措施: Control group (Other)
Erector spinae plane block group
patients will receive general anesthesia and bilateral ultrasound guided erector spinae plane block (20ml Bupivacaine 0.25%)
干预措施: Erector spinae plane block group (Procedure)
Quadratus lumborum block group
patients will receive general anesthesia and bilateral ultrasound guided quadratus lumborum block (20 ml Bupivacaine 0.25%)
干预措施: Quadratus lumborum block group (Procedure)
结局指标
主要结局
The degree of postoperative pain in the first 24 hours post-operative
时间窗: first 24 hours post-operative
Postoperative pain will be assessed by the numerical rating scale (NRS); 0 no pain while 10 is the maximum pain) after discharge to the ward ,and at 6, 12, 18, 24 hours.
次要结局
- Time to first analgesic requirement(first 24 hours post-operative)
- Total dose of intraoperative consumption of fentanyl(intraoperative)
- Total dose of rescue analgesia in the first 24hr postoperative(first 24 hours post-operative)
研究者
Mai Elsaid Hamada
Resident of Anesthesiology, Surgical Intensive Care and Pain Medicine
Tanta University