Pain Neuroscience Education's Effect on Memory and Pain Drawings: An Exploratory Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 主要终点
- Memory Function (Montreal Cognitive Assessment - MoCA)
研究概览
简要总结
Brief Summary:
The goal of this observational study (case series) is to determine whether Pain Neuroscience Education (PNE) can influence memory function and sensory awareness in adults (18 years and older) experiencing chronic pain lasting more than one year.
The main questions it aims to answer are:
Does a single PNE session improve memory performance, as measured by the Montreal Cognitive Assessment (MoCA)?
Does PNE change sensory awareness, as represented by alterations in body pain drawings using a grid overlay method?
Participants will:
Complete pre-intervention assessments, including:
Numeric Pain Rating Scale (NPRS)
Body chart drawing to map pain area
Montreal Cognitive Assessment (MoCA)
Pain Catastrophization Scale (PCS)
Receive a 10-15 minute standardized PNE session delivered by a licensed clinician trained in pain science
Complete the same assessments immediately after the intervention to identify any changes in memory, sensory awareness, and pain perception
This study aims to explore whether PNE can positively impact cognitive and sensory functions affected by chronic pain, beyond its already-established effects on movement and pain intensity.
详细描述
Detailed Description:
Chronic pain is a complex, multidimensional condition affecting approximately 25% of the global population. It is increasingly understood through the lens of brain-based changes, particularly the dynamic pain connectome, a network of brain regions involved in sensory, cognitive, and emotional processing. Functional reorganization in chronic pain patients may contribute to clinical symptoms beyond pain, such as memory loss, decreased sensory awareness, and altered motor control.
Pain Neuroscience Education (PNE) is an educational intervention that aims to reconceptualize a patient's understanding of pain to reduce fear-avoidance, pain catastrophization, and disability. Systematic reviews have demonstrated its effectiveness in reducing pain and improving movement. Early fMRI studies suggest that PNE may also deactivate pain-related brain areas and normalize brain function.
This case series seeks to explore the impact of a single PNE session on cognitive (memory) and sensory (body perception) outcomes in individuals with chronic pain. Participants (aged 18 and older) who meet inclusion criteria and consent to the study will undergo pre- and post-intervention assessments. These include:
Numeric Pain Rating Scale (NPRS)
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 and above
- •Chronic pain > 1 year
- •Provide written consent
- •Proficient in reading and understanding English
排除标准
- •Not willing to participate in the study
- •Have received PNE as a treatment before
结局指标
主要结局
Memory Function (Montreal Cognitive Assessment - MoCA)
时间窗: At baseline (prior to the pain neuroscience education session) and immediately after completion of the treatment session
Description: Change in MoCA score to assess improvement or decline in cognitive function, particularly memory, associated with chronic pain. The MoCA is scored out of 30; a change of 2 points or more is considered clinically meaningful.
Sensory Awareness (Body Chart Pain Area - Grid Overlay Count)
时间窗: At baseline (prior to the pain neuroscience education session) and immediately after completion of the treatment session
Change in the number of grid blocks marked on the body pain chart to quantify alteration in perceived pain area, reflecting somatosensory representation changes.
次要结局
- Self-Reported Pain Intensity (Numeric Pain Rating Scale - NPRS)(At baseline (prior to the pain neuroscience education session) and immediately after completion of the treatment session)
- Pain Catastrophization (Pain Catastrophization Scale - PCS)(At baseline (prior to the pain neuroscience education session) and immediately after completion of the treatment session)