NCT05464823进行中（未招募）不适用
Feasibility of Combined Genomics/Transcriptomics for Patients With Lymphoma
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 111
- 试验地点
- 1
- 主要终点
- Percentage of participants who have genomic test results available in <=7 days
研究概览
简要总结
To learn more about the usefulness of molecular testing with the Molecular Functional (MF) Portrait (a commercial test conducted by the sponsor of this study, BostonGene) in guiding lymphoma care.
详细描述
Primary Objective:
• To determine the feasibility and turnaround of clinical WES and transcriptome sequencing
Secondary Objectives:
- To determine the frequency of actionable DNA and RNA alterations
- To determine the concordance of DNA and RNA alterations
- To determine the frequency of molecularly matched therapy
- To determine the feasibility of identifying mechanism(s) of acquired resistance with genomic profiling
- To determine the feasibility of molecularly matched therapy to acquired resistance alterations
Exploratory Objectives:
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patient Eligibility:
- •Inclusion Criteria:
- •Male/female patients who are at least 18 years of age on the day of informed consent signing.
- •Patients must have a histologically documented diffuse large B-cell lymphoma requiring therapy.
- •Provision of written informed consent for the study.
排除标准
- 未提供
研究组 & 干预措施
Molecular Testing
Other
Molecular Functional (MF) Portrait (a commercial test conducted by the sponsor of this study, BostonGene) in guiding lymphoma care.
干预措施: Molecular Functional Portrait (Other)
结局指标
主要结局
Percentage of participants who have genomic test results available in <=7 days
时间窗: through study completion an average of 1 year
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Biomarkers and Functional Imaging in Predicting Response of Esophageal CancerEsophageal CancerNCT03029793Air Force Military Medical University, China200
Unknown
不适用
Exploratory Study of Molecular Profile-Associated Evidence Guided Precision Therapy for Salivary Gland Cancer（MAPS）Salivary Gland NeoplasmsNCT05087706Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University182
终止
不适用
Functional Image and Molecular Markers to Predict Treatment Outcomes in Lung CancerLung NeoplasmsNCT02117440Indiana University10
已完成
不适用
Stage III NSCLC RWE in Chinese PatientsCarcinoma, Non-Small-Cell LungNCT04023812AstraZeneca500
已完成
不适用
PANORAMA - Real World Molecular Testing, Treatment Patterns, and Clinical Outcomes EGFR Mutation-Positive NSCLCCarcinoma, Non-Small-Cell LungNCT02777658AstraZeneca169