Theory of Mind, Empathy and Eye Gaze Strategies During an Artwork Observation in Neurodegenerative Pathologies.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- 1. Gaze patterns
研究概览
简要总结
Analysis of gaze patterns during social cognition tasks and standardised exploration of a specific artwork, between elderly subjects without cognitive disorders and subjects with neurodegenerative diseases such as Fronto-Temporal Dementia, Alzheimer's Dementia or Parkinson's Disease
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or Female.
- •60 years old and above.
- •Sufficient written and oral expression in French.
- •Benefit from French or Monaco Social security.
- •Written informed consent signed by the patient.
- •For the control group: voluntary subjects, without cognitive impairment.
- •For the FTD / AD / PD groups: patients diagnosed with one of these diseases, and volunteers to participate in the study.
排除标准
- •General anaesthesia within 3 months.
- •Ophthalmological problems preventing a video-oculography examination.
- •Oculomotor disorders such as "fixation disorders" or "ocular tracking disorders".
- •History of stroke.
- •Cognitive disorders of the type: visual agnosia, visuo-spatial disorder, visuo-perceptual disorder or aphasia.
研究组 & 干预措施
Healthy volunteers
20 subjects
干预措施: Eye-Tracking / Neuropsychological evaluations (Other)
Parkinson's Disease
20 subjects
干预措施: Eye-Tracking / Neuropsychological evaluations (Other)
Fronto-temporal Dementia
10 subjects
干预措施: Eye-Tracking / Neuropsychological evaluations (Other)
Alzheimer's Dementia
20 subjects
干预措施: Eye-Tracking / Neuropsychological evaluations (Other)
结局指标
主要结局
1. Gaze patterns
时间窗: baseline
Comparison of gaze patterns between the control group and the pathological groups, during standardized exploration of a specific artwork. Evaluation criteria: difference in the number of fixation
2.Gaze Patterns
时间窗: Baseline
Comparison of gaze patterns between the control group and the pathological groups, during standardized exploration of a specific artwork. Evaluation criteria: difference in exploration strategy (chronology) on target areas.
3.Gaze Patterns
时间窗: Baseline
Comparison of gaze patterns between the control group and the pathological groups, during standardized exploration of a specific artwork. Evaluation criteria: difference in time spent on target areas.
次要结局
- Cognitive Theory of mind during an artwork observation: Score 2(Baseline)
- Cognitive Theory of mind during an artwork observation: Score 1(Baseline)
- Affective empathy: Score 4.(Baseline)
- Affective empathy: The Empathy Quotient (EQ).(Baseline)
- Affective ToM : The Reading the Mind in the Eye test - RME - (Baron-Cohen S at al., 2001)(Baseline)
- Cognitive Theory of mind: TOM-15 a false-belief task to assess cognitive theory of mind(Baseline)
- Affective ToM (Score 3)(Baseline)