Safety and efficacy after multiple carbon-ion radiotherapy for patients with hepatocellular carcinoma - Multiple carbon-ion radiotherapy for patients with hepatocellular carcinoma

Delivering re-irradiation for recurrent hepatocellular carcinoma is challenging because of possible risk of radiation induced liver disease. Here, we evaluated the safety and efficacy of repeated hypofractionated carbon-ion radiotherapy in 60 patients of recurrent hepatocellular carcinoma using 2 or 4 fractions.Repeated extremely hypofractionated carbon-ion radiotherapy proved to be safe with promising outcomes in this study.