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临床试验/NCT03778944
NCT03778944招募中不适用

Renal Graft Functional Enhancement During Donor Anesthesia: A Comparative Study of 3 Modalities

Nazmy Edward Seif1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2018年12月20日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
60
试验地点
1
主要终点
Post-operative creatinine clearance

研究概览

简要总结

Renal transplantation is now recognized as the treatment of choice for patients with end-stage renal disease. An optimum anesthetic regimen should enhance the function and perfusion of the transplanted kidney. The aim of this study is to assess & compare the effectiveness of 3 different modalities in this respect: Mannitol, Dopamine and adequate hydration.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • end-stage renal disease, for living-donor kidney transplantation

排除标准

  • severe cardiac or hepatic dysfunction
  • coagulopathy

结局指标

主要结局

Post-operative creatinine clearance

时间窗: 7 days

Post-operative creatinine clearance level of the transplanted kidney graft is measured in ml/min

次要结局

未报告次要终点

研究者

发起方
Nazmy Edward Seif
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Nazmy Edward Seif

Clinical Professor

Cairo University

研究点 (1)

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