A Prospective Randomized Double Blind Clinical Trial to Assess the Efficacy of Twin Mix and Lidocaine on Inferior Alveolar Nerve Block.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Twin mix may prove to be effective for pulpal anaesthesia in Inferior Alveolar nerve blocks in healthy teeth
研究概览
简要总结
Achieving successful pulpal anaesthesia in healthy mandibular teeth is a challenge for the practitioner, with a success rate of 51-65% . There have been multiple suggestions to improve the anaesthesia:
- Supplementary anaesthesia –
Intraligamentary
Intraosseous
Intrapulpal
2. buccal infiltrations of articaine, ketarol, dexamethasone
- Premedication with analgesics and steroids ( Ibuprofen, Ketarol, Dexamethazone )
Use of steroid as oral, parental and submucosal routes has been extensively studied in third molar impaction surgeries.
One method of delivery suggested is mixing the steroid in the LA solution – TWIN MIX
This mixture has been extensively studied and found to be very effective in third molar extractions.
The efficacy in teeth with pulpal anaesthesia has not been studied.
The aim of this study is to assess the anaesthetic efficacy of twin mix for achieving successful pulpal anaesthesia when used in IANB, and in healthy pulp.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •Age: 18-55 years
- •Currently not feeling pain
- •Good health
- •Not taking any medication that would alter the perception of pain determined by verbal questioning and written questionnaire.
- •Having the first molar, First Premolar and Lateral incisor present.
排除标准
- •Having Pain or irreversible pulpitits
- •Existence of acute infection and/or swelling
- •Systemic disorders
- •History of complications associated with LA.
结局指标
主要结局
Twin mix may prove to be effective for pulpal anaesthesia in Inferior Alveolar nerve blocks in healthy teeth
时间窗: 15 minutes
次要结局
- twin mix may prove more effective than lidocaine in pulpal anaesthesia in mandibular teeth(15 minutes to 60 minutes)