NCT04451928已完成不适用
Prediction of Preterm Delivery by Serum Ischemia Modified Albumin, Biglycan and Decorin Levels in Women With Threatened Preterm Labour
Ismail Biyik1 个研究点 分布在 1 个国家目标入组 51 人开始时间: 2019年12月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- Gestational age at birth
研究概览
简要总结
In this study, the levels of ischemia modified albumin, biglycan and decorin in the serums of pregnant women hospitalized for preterm labor will be examined. Their serum levels will be compared between women having preterm and term delivery. Their accuracy will be asessed in predicting preterm birth.
详细描述
The study will include 90 singleton pregnant women between the ages of 18 and 42 and gestational ages of 24 and 37 weeks.
Inclusion criteria:
- Singleton pregnancy
- Gestational age between 24 and 37 weeks
- Cervical dilatation less than 3 cm and cervical effacement less than 80%
- Uterine contraction ≥3 times at 30 minutes
- Intact amniotic membrane
Excusion criteria:
- Multiple pregnancy
- Preterm premature rupture of membranes
- Abnormal placentation (such as placenta previa)
- Uterin anomaly
- Maternal heart disease
- Inflammatory or infectious disease
- Preeclampsia
- Fetal growth restriction
- Congenital fetal anomaly
- Polyhydramnios
- Acute chorioamnionitis
- Medically induced preterm delivery
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 42 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Singleton pregnancy
- •Gestational age is between 24-37 weeks
- •Cervical dilatation less than 3 cm and cervical effacement less than 80%
- •Uterine contraction ≥3 times at 30 minutes
- •Intact amniotic membrane
排除标准
- •Multiple pregnancy
- •Preterm premature rupture of membranes
- •Abnormal placentation (such as placenta previa)
- •Uterine anomaly
- •Maternal heart disease
- •Inflammatory or infectious disease
- •Preeclampsia
- •Fetal growth restriction
- •Congenital fetal anomaly
- •Polyhydramnios
- •Acute chorioamnionitis
- •Medically induced preterm delivery
结局指标
主要结局
Gestational age at birth
时间窗: December 2019 - January 2021
Preterm: \<37 gestational week Term: ≥37 gestational week
次要结局
- APGAR score(December 2019 - January 2021)
- Mode of delivery(December 2019 - January 2021)
- Hospital admission and delivery interval(December 2019 - January 2021)
研究者
Ismail Biyik
Assistant Professor
Kutahya Health Sciences University
研究点 (1)
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