DRKS00010531招募中未知
Comparison of nasal and bronchial house dust mite (HDM) provocation in childhood.
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt am Main0 个研究点目标入组 65 人开始时间: 2016年5月27日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 65
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- N/a: Single Arm Study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 5 Years 至 24 Years（—）
- 性别
- All
入选标准
- •Diagnosis of mite allergy (skin prick test = 3mm)
- •Known asthma and / or allergic rhinoconjunctivitis
- •Bronchial allergen challenge performed in the preceding 12 weeks
- •exacerbation free interval> 4 weeks before visit 1
- •Written informed consent of the parents and the child / adolescent
排除标准
- •Age <5 years, age> 25 years
- •Exacerbation of asthma within the last 28 days
- •Severe symptoms of allergic rhinitis or relevant deterioration of allergic symptoms
- •Intake of the following drugs before testing: Decongestant nose drops one day, antihistamines three days, nasal steroids 14 days, oral cortisone four weeks, leukotriene antagonists and cromoglycic acid three days before nasal provocation challenge.
- •Adenoids or nasal surgery in the last three months
- •Serious deviation of the nasal septum
- •Other serious diseases (for example, cystic fibrosis, diseases with immunosuppression, malignancies)
- •Pregnancy, lactation
- •Participation in another clinical trial <30 days
- •Inability to understand the scope of the study
研究者
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