Analysis of the Pathophysiology of Frailty Syndrome and Clinical Development of Frailty Within the Framework of the Innovation Fund Project PRÄP-GO (ANA-PRÄP-GO)

简要总结

详细描述

主要结局

次要结局

• Number of Participants with Delirium as Determined by Chart Review(During the hospital stay, an expected average of 1 week)
• Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)(During the hospital stay, an expected average of 1 week)
• Confusion Assessment Method Severity-Score (CAM-S Long Form) in English(During the hospital stay, an expected average of 1 week)
• Ethical aspects(Up to 1 year)
• Findings of Memory consultation(Up to 1 year)
• Neuroimaging(Up to 1 year)
• Demand of health services(Up to 1 year)
• Sarcopenia(Up to 1 year)
• Quality of life(Up to 1 year)
• Cholinesterases 1(Up to 1 year)
• Delirium Rating Scale Revised 98 in English (DRS-R-98)(During the hospital stay, an expected average of 1 week)
• Delirium Severity Scale (CAM-ICU-7) in English(During the hospital stay, an expected average of 1 week)
• Cardiovascular function 2(Up to 1 year)
• Incidence of delirium(During the hospital stay, an expected average of 1 week)
• Nursing Delirium Screening Scale (Nu-DESC)(During the hospital stay, an expected average of 1 week)
• Cardiovascular function 1(Up to 1 year)
• Patient-related outcome measures (PROMS)(Up to 1 year)
• Incidence of cognitive impairment(Up to 1 year)
• Severity of delirium(During the hospital stay, an expected average of 1 week)
• Confusion Assessment Method (CAM)(During the hospital stay, an expected average of 1 week)
• Intensive Care Delirium Screening Checklist (ICDSC)(During the hospital stay, an expected average of 1 week)
• Patient-related experience measures (PREMS)(Up to 1 year)
• Incidence of dementia(Up to 1 year)
• Calf circumference(Up to 1 year)
• Arm circumference(Up to 1 year)
• Number of participants with changes in laboratory values 2(Up to 1 year)
• APOE polymorphisms(Up to 1 year)
• Total interleukin-8(Up to 1 year)
• Delirium days(During the hospital stay, an expected average of 1 week)
• COVID-19(Up to 1 year)
• Patient satisfaction(Up to 1 year)
• Insomnia(Up to 1 year)
• Dental status(Up to 1 year)
• Stress(Up to 1 year)
• Anxiety 1(Up to 1 year)
• Anxiety 2(Up to 1 year)
• Nutritional Status(Up to 1 year)
• Number of participants with changes in laboratory values 1(Up to 1 year)
• Autophagy of platelets(Up to 1 year)
• Biomarker panel(Up to 1 year)
• Vitamin D (cholecalciferol)(Up to 1 year)
• Analysis of urine(Up to 1 year)
• Hip Osteoarthritis Outcome(Up to 1 year)
• Skill management(Up to 1 year)
• Electroencephalography band power(During the hospital stay, an expected average of 1 week)
• Adverse events(Up to 1 year)
• Adherence to Mediterranean diet (MD)(Up to 1 year)
• Psychometric properties of the Meta Memory questionnaire(During the hospital stay, at the beginning of the investigation, an average of two hours.)
• Postoperative complications(Up to 30 days)
• HbA1c(Up to 1 year)
• Cholinesterases 2(Up to 1 year)
• Intracellular pH(Up to 1 year)
• Multiplex gene expression analyzes (neuroinflammation and micro RNA panels)(Up to 1 year)
• Autoantibodies(Up to 1 year)
• Trypotophan metabolites and short-chain fatty acids(Up to 1 year)
• Peripheral Blood Mononuclear Cell(Up to 1 year)
• Protein panel(Up to 1 year)
• Serum albumin(Up to 1 year)
• Sciatica Bothersomeness Index(Up to 1 year)
• Depth of anesthesia(During surgery, an expected average of 2 hours)
• Cytokines(Up to 1 year)
• Chemokines(Up to 1 year)
• Markers immune-brain axis and gut-brain axis(Up to 1 year)
• Analysis of microbiome(Up to 1 year)
• Gait analysis 1(Up to 1 year)
• Gait analysis 2(Up to 1 year)
• Clinical investigation(Up to 1 year)
• Oswestry disability index (ODI)(Up to 1 year)
• Microbiome 1(Up to 1 year)
• Microbiome 2(Up to 1 year)
• Dementia markers(Up to 1 year)
• Biobanks samples(Up to 1 year)
• Range of Motion of the hip/knee(Up to 1 year)
• Hip abduction force (for total hip arthroplasty patients)(Up to 1 year)
• Disabilities of the Arm, Shoulder and Hand Questionnaire (DASH)(Up to 1 year)
• Knee Osteoarthritis Outcome(Up to 1 year)
• Knee extension and flexion force measurement (for total knee arthroplasty patients)(Up to 1 year)
• Back pain(Up to 1 year)
• Modified Japanese orthopaedic association scale(Up to 1 year)
• ASIA Impairment Scale (AIS)(Up to 1 year)
• Leg pain(Up to 1 year)
• Acceptance of participatory decision-making(Up to 1 year)
• Electroencephalography spectral analysis(During the hospital stay, at the beginning of the investigation, an average of one hour.)
• Effect of analgesics(During the hospital stay, an expected average of 1 week)