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临床试验/NL-OMON50660
NL-OMON50660招募中不适用

Gut-to-brain Signalling of Post-Ingestion Nutrients in lean and obese subjects - SPIN trial

Academisch Medisch Centrum0 个研究点目标入组 60 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • Age: 50-70 years for female subjects and 40-70 years for male subjects, for
  • female subjects: postmenopausal, BMI <25 kg/m2 for lean subjects and >30 kg/m2
  • for obese subjects, insulin resistance for obese subjects, stable weight for 3
  • months prior to study inclusion

排除标准

  • Use of any medication except for those related to treatment of components of
  • the metabolic syndrome (not including insulin, oral glucose lowering drugs,
  • alpha- and beta-blockers)
  • Any actual medical condition except for treated hypothyroidism and the
  • metabolic syndrome
  • History of any psychiatric disorder, neurological disorders, eating disorders
  • (anorexia, binge eating, bulimia), alcohol abuse or upper gastrointestinal
  • tract surgery/abnormalities.
  • Intensive sports (>3/week)
  • Restrained eaters
  • XTC, cannabis, amphetamine or cocaine abuse
  • Alcohol abuse (>3 units/day)
  • Occupational radiation exposure
  • Contraindication for MRI
  • Lactose/gluten intolerance
  • Soya oil, egg or peanut allergy
  • Childhood onset of obesity (<4 years)

研究者

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