A COMPARATIVE CLINICAL TRIAL TO EVALUATE THE EFFECT OF VIDANGADI CHOORNA WITH MADHU ALONG WITH LIFESTYLE MODIFICATIONS IN BORDERLINE HIGH DYSLIPIDEMIA
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Changes in Serum Total Cholesterol, LDL Cholesterol,
研究概览
简要总结
Dyslipidemia refers to abnormal amount of lipids and lipoproteins in the blood due to impairment in lipoprotein metabolism and is a major risk factor for development of Coronary artery disease.
It can be correlated in ayurveda as medodushti, associated with kaphadushti and dhatwagni mandya , and as a precursor stage of medoroga and can be easily treated by effective interventions . Treatment of sthoulya can be adopted for Dyslipidemia which includes kaphamedohara, deepana, pachana, rukshana ,lekhana karmas .
A Quasi experimental study will be performed in 64 participants of all sex, satisfying inclusion and exclusion criteria . Out of 64 participants , 32 each will be allocated to Intervention group (Group 1) and Comparison group (Group 2). The participants in the group 1 will be given Vidangadi choorna (6gm )with Madhu (12gm) as anupana after food twice daily along with Lifestyle modification such as dietary modifications and exercise of 30 minutes brisk walking (daily morning). Life style modification alone will be advised to Comparison group. The study period is fixed for 45 days. The serum lipid profile will be analysed before study , on 16th day , 46th day and follow up on 91th day. The data collected will be processed and conclusions will be made accordingly.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •Participants having either or all of serum total cholesterol between 200mg/dL-239mg/dL, LDL 130mg/dL-159mg/dL, Triglycerides 150mg/dL-199mg/dL.
排除标准
- •Participants with Chronic systemic illness under medication Diagnosed case of Diabetes Mellitus On antihpertensive medication or BP greater than 140/90mm Hg Habit of cigarette smoking HDL cholesterol less than 40 mg/dL Family history of Premature Coronary Heart Disease CHD in male first degree relative less than 55 years and CHD in female first degree relative less than 65 years Diagnosed case of Dyslipidemia under medication Pregnant women and lactating mother.
结局指标
主要结局
Changes in Serum Total Cholesterol, LDL Cholesterol,
时间窗: 0th 16th 46th day and follow up on 91st day
Triglycerides, HDL Cholesterol
时间窗: 0th 16th 46th day and follow up on 91st day
次要结局
未报告次要终点
研究者
DR MEGHNA JAGAJEEV
GOVERNMENT AYURVEDA COLLEGE , THIRUVANATHAPURAM