Heart Rate Sensing and Response in Persons With Anorexia Nervosa
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 2
- 主要终点
- Mean percentage of time in prescribed heart rate range during four bouts of interval exercise training
研究概览
简要总结
There are two major goals of this investigation. First, to develop pilot data to justify a larger randomized clinical trial of an intervention designed to train interoceptive signals (IS) and interoceptive responsivity (IR) in persons with Anorexia Nervosa (AN). Second, the investigators will determine whether persons with AN have similar or different IS and IR for heart rate while exercising as compared to age and gender matched controls.
详细描述
The purpose of this pilot investigation is to assess AN interoceptive sensitivity and responsivity as it pertains to heart rate during exercise. Thirty adults, 18 years and older will be recruited for a cross-sectional comparison of IS and IR in the context of exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Study participants will include adults with anorexia spectrum disorders and healthy age and gender matched controls. There will be two control groups, one that includes regularly exercising age and gender matched persons and one where controls do not engage in regular exercise.
- •For those with AN, the following INCLUSION criteria must be met:
- •Age ≥ 18 years old
- •BMI 25 kg/m2 or less
- •Diagnosis of anorexia spectrum disorder
- •Medications: Stable use of all medications ≥ three months
- •For age and gender matched controls, the following INCLUSION criteria must be met:
- •Age ≥ 18 years old
- •BMI 25 kg/m2 or less
- •No diagnosis of anorexia spectrum disorder
- •Medications: Stable use of all medications ≥ three months
- •Age (+/- 2 years) and gender matched to study participant
排除标准
- •History of diabetes, heart disease or taking medications for those conditions
- •History of hypertension (high blood pressure) not controlled with medication
- •Orthopedic limitations, musculoskeletal disease and/or injury
- •Inability to consent
- •Lack of transportation to the Duke Center for Living campus
结局指标
主要结局
Mean percentage of time in prescribed heart rate range during four bouts of interval exercise training
时间窗: Baseline only
One exercise training session
次要结局
未报告次要终点