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临床试验/NCT01330992
NCT01330992已完成不适用

Human Circadian Sensitivity to Very Short Light Pulses

Brigham and Women's Hospital2 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2009年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
400
试验地点
2
主要终点
Circadian Phase (hours)

研究概览

简要总结

The mammalian eye serves both visual and non-image-forming functions. New information about the non-image-forming anatomy and physiology of the eye has revealed effects of ocular light stimuli on human circadian rhythms, melatonin suppression, heart rate, pupillary reflexes, cognitive performance, alertness and sleep. The results of the proposed work can be used to make predictions about the effects of light, to make recommendations involving exposure to or avoidance of light, and to design environmental lighting, resulting in improved health and alertness and decreased errors and accidents.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy volunteers

排除标准

  • No medications
  • No eye disease
  • No sleep disorders
  • No psychiatric disorders

结局指标

主要结局

Circadian Phase (hours)

时间窗: Before and after intervention (day 1)

Circadian phase (hours) measured before and after intervention

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Elizabeth B. Klerman

Associate Professor, Associate Physician

Brigham and Women's Hospital

研究点 (2)

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