Human Circadian Sensitivity to Very Short Light Pulses
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 400
- 试验地点
- 2
- 主要终点
- Circadian Phase (hours)
研究概览
简要总结
The mammalian eye serves both visual and non-image-forming functions. New information about the non-image-forming anatomy and physiology of the eye has revealed effects of ocular light stimuli on human circadian rhythms, melatonin suppression, heart rate, pupillary reflexes, cognitive performance, alertness and sleep. The results of the proposed work can be used to make predictions about the effects of light, to make recommendations involving exposure to or avoidance of light, and to design environmental lighting, resulting in improved health and alertness and decreased errors and accidents.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers
排除标准
- •No medications
- •No eye disease
- •No sleep disorders
- •No psychiatric disorders
结局指标
主要结局
Circadian Phase (hours)
时间窗: Before and after intervention (day 1)
Circadian phase (hours) measured before and after intervention
次要结局
未报告次要终点
研究者
Elizabeth B. Klerman
Associate Professor, Associate Physician
Brigham and Women's Hospital
