The Acute Effect of Vaping on Food Intake
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Energy Intake
研究概览
简要总结
This study assesses the acute effects of a standardized 20-minute vaping episode compared to a non-vaping control condition on ad libitum food intake during a 30-minute buffet meal, occurring approximately 45 minutes after the vaping episode
详细描述
Weight control is a common motive for cigarette smoking and nicotine has been shown to suppress appetite and increase resting metabolic rate, and also serves as a behavioral alternative to eating or a distraction from hunger or food craving. Data on the acute effect of e-cigarette use ('vaping') on ad libitum food intake are non-existent. Given that many e-cigarette users report vaping for weight control and that certain e-cigarettes are being actively marketed for weight management and/or suppression of food cravings, addressing this research gap is of the utmost importance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 - 65 years of age (ID card verified)
- •Reports either everyday e-cigarette use with liquid containing at least 0.3% (~3 mg/ml) nicotine or some day e-cigarette use ( at least 3 days a week) with liquid containing at least 3% (~30 mg/ml) nicotine for the past 30 days.
排除标准
- •being unwilling to consume the foods provided due to: a) dietary limitations or preferences or b) allergies to the foods provided.
- •being unwilling to take 20 puffs from a JUUL device containing a 5% nicotine pod
- •self-reported current, diagnosed medical condition(s) will be excluded automatically: heart-related conditions (e.g., recent heart attack/stroke, coronary heart disease), severe immune system disorders (e.g., HIV/AIDS, multiple sclerosis), respiratory disorders (e.g., COPD, asthma), kidney diseases, liver diseases (e.g., cirrhosis), or seizures
- •observed high blood pressure at screening (systolic >140; diastolic >90)
- •other self-reported current, diagnosed medical conditions (e.g., specific food allergies, diabetes, thyroid disease, lyme disease) will be considered for exclusion after consultation with the PI and medical monitor
- •self-reported current, diagnosed psychiatric conditions or who report current psychiatric treatment or psychotropic medication use
- •past month use of cocaine, opioids, benzodiazepines, methamphetamine, or other (non-cannabis) illicit drugs
- •self-report of >25 days out of the past 30 for alcohol use or >20 days out of the past 30 for cannabis use.
- •women who are breast-feeding or test positive for pregnancy (by urinalysis at screening)
- •women using progestin-IUDS for birth control
- •women using birth control injections (e.g., Depo-Provera)
- •women who received a hysterectomy and still have ovaries present
- •self-report intending to quit tobacco/nicotine products in the next 30 days
结局指标
主要结局
Energy Intake
时间窗: intake was assessed over a 30 minute meal
Energy intake in kilocalories (kcal) during the ad libitum buffet meal will be measured via directly weighed food provision and waste (food/energy intake is calculated by difference).
次要结局
- Dietary Added Sugar Intake(intake was assessed over a 30 minute meal)
- Dietary Carbohydrate Intake(intake was assessed over a 30 minute meal)
- Dietary Sugar Intake(intake was assessed over a 30 minute meal)
- Dietary Fat Intake(intake was assessed over a 30 minute meal)
- Dietary Protein Intake(intake was assessed over a 30 minute meal)
- Dietary Cholesterol Intake(intake was assessed over a 30 minute meal)
- Dietary Fiber Intake(intake was assessed over a 30 minute meal)
- Dietary Potassium Intake(intake was assessed over a 30 minute meal)
- Dietary Saturated Fat Intake(intake was assessed over a 30 minute meal)
- Dietary Vitamin D Intake(intake was assessed over a 30 minute meal)
- Difference in Food Cravings(The FCQ-State was administered about 30 minutes after either the vaping or non-vaping (control) condition and about ~20 minutes before the ad lib buffet meal.)
- Dietary Calcium Intake(intake was assessed over a 30 minute meal)
- Dietary Iron Intake(intake was assessed over a 30 minute meal)
- Dietary Sodium Intake(intake was assessed over a 30 minute meal)