EUCTR2015-002001-11-DE进行中（未招募）1 期
A Phase II Open-Label, Multi-Center Study of MEDI4736 Evaluated as Single Agent or in Combination with Tremelimumab in Patients with Metastatic Pancreatic Ductal Adenocarcinoma - ALPS
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 130
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1.Histologically or cytologically confirmed metastatic PDAC, no more than 1 prior chemotherapy regimen
- •2. ECOG 0 or 1
- •3. At least 1 lesion, not previously irradiated, that can be accurately measured at
- •baseline as =10 mm in the longest diameter (except lymph nodes, which must have short axis =15 mm) with computed tomography (CT) or magnetic resonance imaging (MRI) scan and that is suitable for accurate repeated measurements
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 91
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 39
排除标准
- •1.Any concurrent chemotherapy, IP, biologic, or hormonal therapy for cancer
- •2. History of leptomeningeal carcinomatosis
- •3. Ascites requiring intervention
- •4. Brain metastases or spinal cord compression.
研究者
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