Impact of Post-Traumatic Stress Disorder Treatment by Reconsolidation Therapy on Fibromyalgia Syndrome - PTSD-FMS

Henri Laborit Hospital0 个研究点目标入组 25 人开始时间: 2021年3月24日最近更新: 2024年6月18日

适应症

试验速览

暂无简介。

•- Adult over 18 years old
•- Diagnosis of fibromyalgia syndrome according to ACR 2016 criteria
•-PCL-5 > 44 suggesting the presence of a comorbid post-traumatic stress disorder
•-Meet the DSM-5 criteria for post-traumatic stress disorder secondary to exposure to a traumatic event according to DSM-5 criteria, both unique or repeated and regardless of the date or location of the traumatic event.
•-Pain relief treatment and/or psychotropic treatment stabilized for a period greater than or equal to two months.
•-Signature of a consent form
•-Patient able to understand and read french
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 20
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 5

•-Psychotic disorders
•-Unstable bipolar disorder
•-Patients with a systolic blood pressure < 100 mmHg or heart rate < 55 as established during the initial visit
•-Significant anormal ECG
•-Medical contraindication to taking propranolol
•-Adverse reactions or previous intolerances to a beta blocker
•-Current intake of another beta blocker which can not be stopped during the protocol, regardeless the galenic.
•-Current intake of a drug with potential contraindication with the propranolol, according to the summary of product characteristics of the propranolol.
•-Patient under legal protection, under guardianship or under curatorship
•-Patient having suffered a head trauma for less than a year or with clinical symptoms and neurological sequelae
•-Known severe suicide risk (MINI-S and medical exam)
•-Current opioid addiction or alcohol dependence
•-Patients treated for less than 2 months with antidepressants or painkillers
•-Patients unafiliated to a social health care
•-Woman who is pregnant or breast-feeding or whithout efficient contraception

发起方

Henri Laborit Hospital