跳至主要内容
临床试验/CTRI/2021/02/031412
CTRI/2021/02/031412尚未招募不适用

A Comparative study of actual mortality rate with standardised mortality rate calculated by APACHE-IV and SAPS-II in severe sepsis and septic shock patients: A prospective observational study.

Swarnika Singh1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2021年2月24日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
50
试验地点
1
主要终点
To compare the accuracy of the APACHE IV and SAPS II scoring system in predicting mortality rate among patients admitted with severe sepsis and septic shock in our ICU

研究概览

简要总结

Sepsis is defined as life threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis remains an important cause of ICU admission, and despite advances in antibiotics and refined supportive care, mortality due to sepsis remains leading cause of death in non-coronary ICU.

There are several scoring system which have been developed to calculate and predict the mortality rate in critically ill patients.

APACHE is the first scoring system used to determine the prognosis of the patient. SAPS scoring system was developed later. SAPS-II is the most widely used scoring system in European  ICU.

we are aiming to calculate the predicted mortality rate, with the help of two scoring systems, APACHE-IV and SAPS-II, and compare it with the actual mortality rate encountered in our ICU.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patients admitted in Medical ICU meeting the diagnostic criteria for severe sepsis and septic shock during the first 24 hr of admission will be included in our study.

排除标准

  • 1.Patient/patient’s party refuse to participate, 2.Age <18 years and >70 years.
  • 3.Patients whose duration of stay in ICU was less than 4 h.

结局指标

主要结局

To compare the accuracy of the APACHE IV and SAPS II scoring system in predicting mortality rate among patients admitted with severe sepsis and septic shock in our ICU

时间窗: length of stay in ICU

次要结局

  • 1.To calculate predicted mortality rate using APACHE-IV Scoring System in patients of severe sepsis and septic shock.(2. To calculate predicted mortality rate using SAPS-II Scoring System in patients of severe sepsis and septic shock.)

研究者

发起方
Swarnika Singh
申办方类型
Government medical college

研究点 (1)

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