Comparing Eye Pressure Using Maximal Tolerated Local Therapy or Systemic Acetazolamide. A Possible Pretreatment for Trabeculectomy Surgery.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 试验地点
- 1
- 主要终点
- Eye pressure
研究概览
简要总结
Local therapy for glaucoma is known to induce a conjunctival inflammation. Because of this, trabeculectomy is more likely to fail. The investigators exchange the local therapy by systemic therapy using acetazolamide and measure the eye pressure using local therapy and systemic therapy using acetazolamide. The investigators suspect an elevated eye pressure using acetazolamide compared to local therapy. In summary acetazolamide could be a better choice in reference to conjunctival inflammation, but a worse choice in reference to controlling eye pressure.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with uncontrolled intraocular eye pressure
- •Patients with planed trabeculectomy in 3 to 4 weeks
排除标准
- •Patients not meeting the inclusion criteria
- •Patients with known intolerance to acetazolamide
研究组 & 干预措施
Patient with a trabeculectomy planed
干预措施: Acetazolamide for glaucoma patients to lower eye pressure (Drug)
结局指标
主要结局
Eye pressure
时间窗: Once at the beginning of the study and once 3 to 4 weeks later
The eye pressure is measured at the beginning of the study, when the patient is using the maximal tolerated local therapy and 3 to 4 weeks later, when using systemic acetazolamide treatment.
次要结局
未报告次要终点