NCT04799340招募中不适用
Characterizing and Remediating Recollection-specific Face Recognition Deficits in Developmental Prosopagnosia
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Cambridge Face Memory Test
研究概览
简要总结
This study will examine the effectiveness of a cognitive training intervention targeting face recollection, repetition lag training, at improving face recognition in Developmental Prosopagnosia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Developmental prosopagnosic participants will be included if they are...
- •aged 18-90,
- •have lifelong histories of face recognition difficulties that impact their everyday life (i.e., not associated with some event such as a stroke, seizure, etc)
- •score significantly below the mean on the famous faces test and Cambridge Face Memory Test
排除标准
- •Participants will be excluded from the study if they...
- •have a history of a significant neurological disorder including hydrocephalus, stroke, moderate to severe traumatic brain injury (TBI), severe neuromuscular diseases, or severe hypoxia due to cardiac arrest.
- •have impairments that interfere with cognitive performance, such as uncorrected hearing or vision, lack of English proficiency, musculoskeletal or other issues
- •have psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, chronic intractable obsessive-compulsive disorder, or agoraphobia.
- •We will exclude individuals who are currently dependent on alcohol or other substances, as this may negatively impact cognitive performance.
- •We will exclude participants who currently are, or within the last 6 months, participating in a behavioral or pharmacological intervention.
- •Patients with a history of mild TBI or simple concussion will not be excluded as long as it was > 6 months ago and as long as they have not had repeated concussions (>5)
- •We will include individuals with a diagnosis of ADHD as long as their medication has been consistent for the past 6 months.
研究组 & 干预措施
holistic face training + repetition lag training
Experimental
干预措施: cognitive training (Behavioral)
waitlist control
No Intervention
结局指标
主要结局
Cambridge Face Memory Test
时间窗: 15 minutes
learning and recognizing novel faces, out of 72 (higher score is better)
Face Perception
时间窗: 30 minutes
composite of face matching tasks, Cambridge Face perception Test and computerized Benton, higher score is better
Face Recollection
时间窗: 15 minutes
old/new face recognition test, extracting familiarity and recollection parameters, higher score is better
次要结局
- Face-name learning task(15 minutes)
- Self-reported face recognition(5 minutes)
研究者
Joseph DeGutis
Assistant Professor
Harvard Medical School (HMS and HSDM)
研究点 (1)
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