NCT01517425Enrolling By Invitation不适用
Evaluating Cardiovascular Phenotypes Using Induced Pluripotent Stem Cells
Scripps Translational Science Institute1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2012年11月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- iPSC development
研究概览
简要总结
This research is being done to understand how changes in DNA may put people at risk for developing coronary artery disease. Stem cells will be made using cells from blood and/or skin biopsy samples. We are trying to understand which specific changes in DNA negatively impact a person's health.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Previously enrolled in the CAD module of the Genebank at Scripps Clinic Registry
- •Eligible to have their blood drawn
- •Be reliable, cooperative and willing to comply with all protocol-specified procedures
- •Able to understand and grant informed consent
- •Previously enrolled in the Healthy Elderly Active Longevity (HEAL) Cohort
- •Eligible to have their blood drawn
- •Be reliable, cooperative and willing to comply with all protocol-specified procedures
- •Able to understand and grant informed consent
排除标准
- •Unwilling or unable to grant informed consent.
- •Have a significant medical condition that in the Investigator's opinion may interfere with subject's study participation.
结局指标
主要结局
iPSC development
时间窗: five years
Develop methods of iPSC generation from patients with genomic risk.
次要结局
未报告次要终点
研究者
Eric Topol, MD
Director, Scripps Translational Science Institute
Scripps Translational Science Institute
研究点 (1)
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