a randomized, double blind, comparative study of oral metronidazole and tinidazole in treatment of bacterial vaginosis
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- compare the cure rate of oral metronidazol with tinidazol
研究概览
简要总结
Bacerial vaginosis is a clinical syndrome of unknown etiology characterized by y over growth of vaginal anaerobes such as Gardenella vaginalis, bacteroids, mycoplasma. It is the commonest form of lower reproductive tract infection. currently metronidazole is considered as the drug of choice with cure rate of 77.9% . there are also studies showing effecac of tinidazole in treating bacterial vaginosis. it is better tolerated compared to metronidazole. this study is aiming in comparing the cure rates of metronidazole an tinidazole. as secondary endpoint we are comparing the safety profile in both the groups
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Female
入选标准
- •women diagnosed with bacterial vaginosis.
排除标准
- •pregnant and lactating mothers, history of smoking and alcohol, previous history of bactrial vaginosis, with STDs, HIV or genital malignancies, antimicrobial use in previous 14 days.
结局指标
主要结局
compare the cure rate of oral metronidazol with tinidazol
时间窗: compare the cure rate at the end of 5 days of oral metronidazol with tinidazol
次要结局
- compare adverse effects of metronidazol with tinidazol(5days)