an Audit on Postoperative Variations in Anemia Treatment After Major Gynecological Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- the rate of anemia after major gynecological surgery
研究概览
简要总结
The study aims to increase our understanding of variability in adherence to anaemia management guidelines and to assess the impact of anaemia management in clinical care following major gynaecological surgery
详细描述
Anemia affects nearly a quarter of the world and is common in surgical patients with a third of patients presenting with preoperative anemia and three quarters of patients discharged from hospital with anemia. The World Health Organization defines anemia as an insufficient circulating red cell mass, with haemoglobin (Hb) concentration of < 130 g.l-1 for men and < 120 g.l-1 for women .
Perioperative anemia is associated with increased postoperative complications and delayed patient recovery leading to increased post-operative morbidity and mortality. Anaemia also leads to an increased use of allogeneic blood transfusions, which is an independent risk for poorer patient outcomes.
Postoperative anemia can be due to blood loss at operation or secondary to the inflammatory process associated with surgery, which causes an increase in hepcidin production resulting in functional iron deficiency and reduced red cell production.
In recent years, there has been a significant increase in the use of intravenous iron therapy for preoperative anemia in line with major international guidelines
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age: Adult, 18_60 years
- •Procedure: A major gynecological surgery is defined as an operation with an incision into the abdominal cavity and anticipated duration of more than one hour. Procedures performed using any surgical approach, including open and laparoscopic surgery are included.
- •Urgency: Patients undergoing planned (elective or expedited) or unplanned (emergency) surgery
排除标准
- •Procedures: surgery classified as minor operations such as; diagnostic laparoscopy (emergency or elective), D&C.
- •Indication: Palliative procedures as determined pre-operatively and explicitly stated in the medical record or consent form.
- •Return to theatre: Each patient should only be included in the study once. Patients returning to theatre due to complications following earlier surgery
结局指标
主要结局
the rate of anemia after major gynecological surgery
时间窗: one month
percentage of patients with anemia after surgery
次要结局
未报告次要终点
研究者
Yossra G. Rateb
principal investigator
Assiut University