Effect of External Pressure and Muscle Contraction on Soft Tissue Oxygenation Measured With Functional MRI
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 入组人数
- 75
- 试验地点
- 2
研究概览
简要总结
Demonstration of soft tissue hypoxia on MRI using external compression and muscle contraction.
详细描述
Participant will undergo a single MRI examination. Standard orthopedic Sarmiento brace/ shell applied to participant's arm. Inside the brace will be a standard blood pressure cuff with a standard brace soft foam attached; blood pressure cuff will be partially inflated. Participant will also be asked to lift MRI compatible 10 lb. weight. Muscle oxygenation will be actively measured using MRI. No medications are being given, and no invasive devices are being used.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Alert and oriented.
- •Able to lift 10lbs. and hold for 30 seconds
- •Not claustrophobic.
- •Intact sensation in right upper extremity.
排除标准
- •Latex allergy or allergy to isopropyl alcohol.
- •Skin injury or decreased sensation on right upper extremity.
研究组 & 干预措施
MRI
Participant will undergo a single MRI examination of arm with no contrast.
干预措施: Compression and Contraction (Procedure)
研究者
Yudell Edelstein
Clinical associate professor
Icahn School of Medicine at Mount Sinai