Encapsulation of Lactobacillus rhamnosus probiotic bacteria by electrospinning method using ploy di actelene polymer.

Islamic Azad University0 个研究点目标入组 25 人开始时间: 待定最近更新: 2023年10月16日

适应症

试验速览

暂无简介。

•The main conditions for entering the study before randomization: patients will be selected based on the Rome II criteria according to the diagnosis of digestive and liver diseases; (Rome II criteria: abdominal pain or any digestive discomfort for at least 3 months during a year) The past three months can be consecutive or non-consecutive, along with two of the following three: resolution of pain with defecation, onset of symptoms with change in frequency of defecation, onset of symptoms with change in stool shape) minimum age 18 years of informed consent of the patient, which is adopted in writing after providing all the necessary explanations for them.

•The main conditions of non-entry into the study before randomization: a history of major gastrointestinal surgery, chronic use of antibiotics, corticosteroids, and immunosuppressive drugs, regular use of drugs that change the movements of the digestive system, such as metoclopramide, cisapride, domperidone, narcotics, especially Opioid derivatives, laxative agents, antidiarrheal agents, and other drugs effective in the treatment of IBS, which are described in more detail in the text. The presence of severe mental and behavioral disorders in the patient, the presence of food allergies, the presence of any organic intestinal disease or chronic digestive disease

发起方