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临床试验/NCT03040505
NCT03040505终止不适用

Future Mental Projections in Schizophrenia

University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2017年4月5日最近更新:
适应症

试验速览

阶段
不适用
状态
终止
发起方
入组人数
56
试验地点
1
主要终点
Number of time location strategies

研究概览

简要总结

The aim of the study is to investigate temporal organization of future thinking in patients with schizophrenia. Patients and control participants will be asked to envision and briefly describe ten personal future events using a cue-words list. Then they will be asked to describe everything that came to their minds (i.e. to think aloud) while they attempted to determine when an event will likely occur. The investigators will compare the proportion of several predefined strategies mentioned by the two groups of participants to locate future events in time. The investigators predict that patients will envision less personal future events and will rely to a lesser extent on strategies to locate events in time, than control participants.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • for patients only
  • male or female
  • age limits : 18-55 years old
  • under the protection of health insurance
  • who have signed up the consent form
  • schizophrenia or schizo-affective disorder according to the DSM-5 criteria (APA, 2013).
  • clinically stable for at least 2 months
  • patients under guardianship or curatorship need agreement of their legal representative
  • informed of the results of prior medical examination for controls only
  • male or female
  • age limits : 18-55 years old
  • under the protection of health insurance
  • who have sign up the consent form
  • recruited from the general population and matched on gender, age years of schooling
  • no psychiatric history (DSM-5)

排除标准

  • for both patients and controls
  • current severe or unstable somatic illness
  • neurological history (brain injury > 15 minutes loss of consciousness , epilepsia, brain surgery...)
  • current substance use disorder (DSM-5)
  • current major depressive disorder (CDSS,BDI, HDRS)
  • mental retardation (IQ < 70, WAIS-4, f-NART)
  • history of general anesthesia 3 months prior to the experiment
  • pregnancy declared by the subject
  • breast feeding
  • current legal control
  • in emergency situation
  • included during exclusion period in another experiment
  • for controls only
  • taking of antipsychotic drugs for the 3 weeks prior to inclusion
  • under guardianship or curatorship

结局指标

主要结局

Number of time location strategies

时间窗: 1 months

次要结局

未报告次要终点

研究者

发起方
University Hospital, Strasbourg, France
申办方类型
Other
责任方
Sponsor

研究点 (1)

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