Reliability of Utrasonographic Diameter of Optic Nerve Sheath in Assessment of Fluid Status in Severe Preeclamptic Patients
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- correlation between optic nerve sheath diameter and extravascular lung water
研究概览
简要总结
Changes in the optic nerve sheath diameter detected by ultrasound are considered an important manifestation of increased intracranial pressure . The normal optic nerve sheath diameter measures up to 5.0 mm and an average optic nerve sheath diameter more than 5 mm is considered abnormal and elevated intracranial pressure should be suspected.Cerebral edema have been demonstrated in 71% to 100% of magnetic resonance imaging in preeclamptic patients and an increase in optic nerve sheath diameter has been described in preeclamptic females compared to healthy pregnant females Therefore, Increased optic nerve sheath diameter can indirectly reflect the state of intracranial edema that could be a part of generalized edema of preeclampsia and it could be a possible marker of generalized tissue edema and fluid overload in these patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Systolic blood pressure of 160mm Hg or higher, or diastolic blood pressure of 110mm Hg or higher on 2 occasions at least 6 hours apart on bed rest.
- •Proteinuria ≥5g in a 24 hour urine specimen or ≥3+ on 2 random urine samples collected at least 4 hours apart.
- •patient acceptance
- •Accepted mental state of the patients
排除标准
- •patient refusal to participate in the study
- •chronic kidney disease
- •chronic pulmonary disease
- •chronic cardiac disease
- •chronic hypertension
- •previous ocular operation and diseases
结局指标
主要结局
correlation between optic nerve sheath diameter and extravascular lung water
时间窗: up to 24 hours
correlation between ultrasound assessment of optic nerve sheath diameter and extravascular lung water
次要结局
未报告次要终点
研究者
Hossam Eldin Hassan Ahmed
assisstant lecturer of anesthesia and ICU ,faculty of medicine at sohag university
Sohag University