Effect of Natural Compounds on the Severity of HPV-induced Cervical Lesions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Regression of cervical lesions
研究概览
简要总结
To test the efficacy of a newly-commercialized formula, 40 HPV-positive women displaying chronic cervicitis, mild dysplasia or moderate dysplasia. Women in the study group took one tablet per day containing 200 mg of EGCG, 400 mcg of Folic Acid, 1 mg of Vitamin B12 and 50 mg of Hyaluronic Acid for twelve weeks. Women in the control group received no treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •HPV infections
- •Occurrence of low-grade cervical lesions
排除标准
- •Diagnosis of malignancy or severe cervical lesions
- •Concurrent uterine pathologies
- •Pregnancy or intended to seek pregnancy in the next three months
研究组 & 干预措施
Co-treatment with EGCG, FA, B12, and HA
One tablet per day containing 200 mg of EGCG, 400 mcg of Folic Acid, 1 mg of Vitamin B12 and 50 mg of Hyaluronic Acid for twelve weeks.
干预措施: Epigallocatechin gallate, Folic acid, Vitamin B12, and Hyaluronic Acid (Dietary Supplement)
Control
Untreated women.
结局指标
主要结局
Regression of cervical lesions
时间窗: 12 weeks
The actual outcome was to measure the rate of regression of the lesions, from moderate to mild, from mild to none.
次要结局
未报告次要终点