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临床试验/NCT04576273
NCT04576273已完成不适用

Enterobius Vermicularis in Appendectomy Specimens; Clinicopathological Assessment

Al-Azhar University1 个研究点 分布在 1 个国家目标入组 1,150 人开始时间: 2017年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,150
试验地点
1
主要终点
Incidence of Appendiceal Enterobius vermicularis

研究概览

简要总结

This study identifies the incidence of appendiceal Enterobius vermicularis (E.v) infestation in all the patients undergoing appendectomy and evaluates the relationship between E.v infestation of the appendix and the acute appendicitis.

详细描述

All the patients undergoing appendectomy surgical procedure for clinical picture of acute appendicitis in 3-years period at our referral hospital were evaluated to pick up the Enterobius vermicularis infestation of the appendix. These cases were evaluated for clinico-laboratory characterization to define the incidence in our country and the relationship between the E.v and initiation of the the inflammatory process to study the possibility of limitation of surgical intervention in acute abdomen conditions.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
4 Years 至 90 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All routine examined appendectomy specimens

排除标准

  • Cases with clinical suspicion of tumor Cases attached to the colectomy specimens

结局指标

主要结局

Incidence of Appendiceal Enterobius vermicularis

时间窗: 3 years

An incidence of Enterobius infestation will be assessed by studying all the received specimens during a 3 years-period using formatting a master sheet and processing in Excel program

Association between acute inflammation and Enterobius vermicularis infestation

时间窗: 3 years

All the studied Enterobius vermicularis cases will be evaluated microscopically to record the count of acute inflammatory cells per millimeter (mm) and per High Power Field (HPF) using the microscope scale measurement. This count will be compared with the inflamed appendectomy specimens without Enterobius infestation to assess the hypothesis of the association between the Enterobius infestation and the acute appendicitis. Also special stain (congo red) will be implicated in some indicated cases to detect eosinophils, eosinophils will be positively staines (orange color stain means positive) if the stain is faint that means negative and the cell is not eosinophil

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Aabdulkarim Hasan

Lab Director

Al-Azhar University

研究点 (1)

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