A Randomized Comparative Clinical Study On Pathyadi Kwatha Nasya And Pathyadi Kwatha Pana In The Management Of Ardhavbhedaka With Special Reference To Migraine
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Improvement in subjective parameters of Ardhavbhedaka
研究概览
简要总结
The proposed study is a randomized, open-label, comparative clinical trial designed to evaluate and compare the efficacy of Pathyadi Kwatha Nasya and Pathyadi Kwatha Pana in the management of Ardhavbhedaka (Migraine). Ardhavbhedaka, described in classical Ayurvedic texts as a severe unilateral headache involving the Manya, Bhru, Shankha, Karna, Akshi, and Lalata regions, closely correlates with migraine in contemporary medicine. Given the rising prevalence of migraine and limitations of modern pharmacotherapy, this study aims to explore safe and holistic Ayurvedic interventions. Thirty patients fulfilling diagnostic criteria will be randomly allocated into two groups—Group A receiving Pathyadi Kwatha Nasya and Group B receiving Pathyadi Kwatha Pana for 30 days. Assessment will be conducted using validated subjective parameters including severity, frequency, duration of headache, nausea, vomiting, vertigo, and aura. Outcomes will be analyzed statistically to determine therapeutic effectiveness and comparative superiority, thereby contributing to evidence-based management of Ardhavbhedaka through Ayurveda.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients of either sex of age between 18 years to 60 years.
- •2.Patients with clinical features of Ardhavbhedaka i.e.Headache,Nausea ,Vomitting,Aura.
- •3.Patients with Chronicity of disease more than 6 months and less than 3 years.
- •4.Patients willing to participate and able to provide signed informed consent.
排除标准
- •1.Patients who are suffering from Hypertension, Diabetes Mellitus and likewise other Chronic diseases.
- •2.Patients suffering from Cervical Spondolysis,Middle ear infections,Trigeminal Neuralgia and Refractive error.
- •3.Patients suffering from Fever,Sinusitis.
- •4.Patients suffering from Secondary Headaches caused by Meningitis,Tumour Encephalitis.
- •5.Patients with history of Head injury and Brain Infections.
结局指标
主要结局
Improvement in subjective parameters of Ardhavbhedaka
时间窗: Assessment: Percentage relief in symptoms and signs after 30 days of | treatment.
Subjective:1.Severity of headache.
时间窗: Assessment: Percentage relief in symptoms and signs after 30 days of | treatment.
2.Frequency of Headache : Assessed in terms of Frequency in days
时间窗: Assessment: Percentage relief in symptoms and signs after 30 days of | treatment.
3.Duration of Headache : Assessed in terms of Hours/day
时间窗: Assessment: Percentage relief in symptoms and signs after 30 days of | treatment.
4.Nausea
时间窗: Assessment: Percentage relief in symptoms and signs after 30 days of | treatment.
5.Vomiting
时间窗: Assessment: Percentage relief in symptoms and signs after 30 days of | treatment.
6.Vertigo
时间窗: Assessment: Percentage relief in symptoms and signs after 30 days of | treatment.
7.Aura
时间窗: Assessment: Percentage relief in symptoms and signs after 30 days of | treatment.
次要结局
- 1.Overall Percentage Improvement Score(2.Patient-Reported Quality of Life Improvement)
研究者
Dr Aditi Sharma
Jammu Institute Of Ayurveda And Research