A Study on the Prospective Cohort Library of Novel Coronavirus Pneumonia in Southeran
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 504
- 试验地点
- 2
- 主要终点
- 36-Item Short Form Survey Instrument (SF-36)
研究概览
简要总结
This is a multi-centre population-based follow-up study for all 504 patients with laboratory-confirmed COVID-19. This study establishes a standardized and structured clinical database to provide complete and multidimensional clinical diagnosis and treatment data of novel coronavirus pneumonia, which also support future epidemiological, infectious disease study and patients' prognosis, by collecting clinical data and the related data of patients with novel coronavirus pneumonia in Southern Zhejiang province.
详细描述
The follow-up information will be collected in one-month, three-month, six-month and one-year after discharge. Information about symptoms, radiographic and laboratory findings, lung function, SF-36 QUESTIONNAIRE, antibody of COVID19，result of RT-PCR Test and suvival information will be collected through all time frames.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with laboratory-confirmed COVID-19 in Wenzhou
排除标准
- •Suspected cases of COVID-19
结局指标
主要结局
36-Item Short Form Survey Instrument (SF-36)
时间窗: one month, three month, six month and one year after discharge, minimum score
sum score of SF 36 form in each time frame
the value of FEV1 by lung function test
时间窗: one month, three month, six month and one year after discharge
the ratio of FEV1 to FVC by lung function test
时间窗: one month, three month, six month and one year after discharge
次要结局
- the predicted ratio of FEV1 to FVC by lung function test(one month, three month, six month and one year after discharge)
- the proportion of applying ACEIs/ARBs medication(from the date of hospital admission to the day of hospital discharge)
- DDI value(one month, three month, six month and one year after discharge)
- the predicted value of FEV1 by lung function test(one month, three month, six month and one year after discharge)
- Lymphocyte value(one month, three month, six month and one year after discharge)
- Number of positive outcome of IgG for antibody of COVID-19(one month, three month, six month and one year after discharge)
- number of cases returning to positive result in RT-PCR test(one month, three month, six month and one year after discharge)
- Neutrophil value(one month, three month, six month and one year after discharge)
- number of clinical symptoms after hospital discharge(one month, three month, six month and one year after discharge)
研究者
Xiaokun Li
Professor
Wenzhou Medical University