The Real-time Optical Diagnosis Value of Optical Enhancement Endoscopy in Colorectal Sessile Serrated Adenomas/Polyps :A Prospective Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Real-time diagnosis accuracy of optical enhancement in colorectal sessile serrated adenomas/polyps
研究概览
简要总结
When a polyp is found, we begin to wash it and observe it with OE mode 1.Then,the endoscopist gives a real-time optical diagnosis and the future surveillance interval.Finally,the polyp will be resected for the biopsy.
详细描述
When discovering a polyp, the endoscopist uses water to wash it.Then, the endoscopist starts with i-scan 1 (OE mode 1) to observe the polyp closely .Nextly, the endoscopist give a real-time optical diagnosis with the blind of the history of patient. Considering the other polyps, the endoscopist gives a surveillance interval predictions according to the guide made by USMSTF.The confidence of the real-time optical diagnosis is divided into high confidence and low confidence.After the observation, the small and diminutive polyp will be resected and have the blinded pathology.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The high risk for colorectal cancer screening score
- •Patients with colorectal polyps reviewing
排除标准
- •1.Inflammatory bowel disease
- •Polyposis syndrome
- •A history of colorectal cancer or surgical resection
- •Poor bowel preparation5.Not signing the informed consent 6.Severe cardiopulmonary function failure lesions, severe hypertension, cerebrovascular disease, mental disorder and coma, pregnancy, lactation can't taking the colonoscopy.
结局指标
主要结局
Real-time diagnosis accuracy of optical enhancement in colorectal sessile serrated adenomas/polyps
时间窗: 2years
次要结局
- Real-time diagnosis accuracy of optical enhancement in colorectal adenomas and hyperplastic polyps(2 years)
研究者
Yanqing Li
Vice president of Qilu Hospital
Shandong University