Comparison between erector spinae plane block versus serratus anterior plane block regarding analgesia and stress response after modified radical mastectomy.

helwan university0 个研究点目标入组 60 人开始时间: 2023年9月6日最近更新: 2024年3月4日

适应症

试验速览

暂无简介。

•Female patients
•Type of surgery; Modified Radical Mastectomy MRM
•Physical status: ASA I and ASA II.
•Age = 35 and = 60 Years in order to standardize doses of anesthetics and decrease age group difference in responses.
•Body mass index (BMI): = 20 kg/m2 and = 35 kg/m2.

•Patient refusal
•Known sensitivity or contraindication to drugs used in the study (local anesthetics, opioids). History of psychological disorders and/or chronic pain syndrome.
•Contraindication to regional anesthesia e.g. local sepsis, pre-existing peripheral neuropathies, coagulopathy and clinical skin infiltration by the tumor.
•Severe respiratory e.g. (sever obstructive pulmonary disease (forced expiratory volume /forced vital capacity FEV1/FVC <50% or sever restrictive pulmonary disease (total lung capacity TLC<40%), adult respiratory distress syndrome) or sever cardiac disorders e.g. (heart failure). (Martinez-Pitre, Sabbula and Cascella, 2021)
•Advanced liver disease (Elevated liver enzymes more than 3 folds of normal range).
•Advanced kidney disease (Decreased creatinine clearance <40 ml/min). (Stevens et al., 2006)

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