AnAnkle Trial: Peripheral nerve block vs. spinal anaesthesia for ankle fracture surgery – implications on pain profile and quality of recovery - AnAnkle Trial

Herlev Hospital, Department of Anaesthesiology I65N90 个研究点开始时间: 2015年3月19日最近更新: 2017年7月3日

试验速览

暂无简介。

•-Patients > 18 years old scheduled for internal fixation of an ankle fracture (malleolar fracture).
•-Ability to read and understand Danish and give informed oral and written consent.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 100
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 50

•-Allergy towards any drug in trial protocol
•-Bodyweight < 52 kg
•-Contraindications for SA according to national guidelines
•-Current gastro-intestinal bleeding
•-Proximal fibular fracture or multitrauma/other fractures
•-Cognitive or psychiatric dysfunction or alcohol/narcotic substance abuse causing expected inability to comply with study protocol as evaluated by anaesthesiologist/investigator
•-No available anaesthesiologist with PNB capability at scheduled time of operation
•-Neuropathy / neurological dysfunction in the lower extremities
•-Habitual daily use of opioids
•-Pregnancy (known or suspected) or breastfeeding
•-Infection at anaesthesia injection site
•-Nephropathy requiring dialysis
•-Acute porphyria

发起方

Herlev Hospital, Department of Anaesthesiology I65N9