Hyperpolarized xenon lung MRI in long-term COVID19

Aarhus University0 个研究点目标入组 32 人开始时间: 2021年12月22日最近更新: 2022年3月14日

试验速览

暂无简介。

•Long COVID19 group:
•Aged 18 – 85 years.
•Pre-menopausal women must be confirmed non-pregnant by an onsite test.
•Previous COVID-19 confirmed with PCR or antibody test.
•Persistent long COVID-19 symptoms
•oFatigue, chest pain, dyspnea or tachycardia
•oMRC dyspnea score above 2.
•oSymptoms not explained by other diseases after work-up at the long-term COVID19 clinic.
•Previous COVID19 group without symptoms:
•Aged 18 – 85 years.
•Pre-menopausal women must be confirmed non-pregnant by an onsite test.
•Previous COVID-19 confirmed with PCR or antibody test.
•No persistent long COVID-19 symptoms.
•Healthy volunteers:
•Aged 18 – 85 years.
•Pre-menopausal women must be confirmed non-pregnant by an onsite test.
•No history of COVID-19.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 25
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 7

•Smoker (ever and current).
•A history of pulmonary embolism.
•Contraindications for MRI:
•-Pacemaker, neurostimulator or cochlear implant
•-Metal foreign bodies such as fragments and irremovable piercings
•-Unsafe medical implants (safety of heart valves, hips and the like must be confirmed)
•-Intracranial clips or coils
•-Cardiac pacemakers
•-Claustrophobia
•-Largest circumference including arms > 160 cm
•Competing pulmonary or systemic diseases.
•-Mild asthma is allowed (no recent oral steroids, no recent admission, monotreatment).
•Allergy to xenon

发起方