KCT0002935已完成未知
Ticagrelor Monotherapy after 3 months in the Patients treated with New Generation Sirolimus-Eluting Stents for Acute Coronary Syndrome
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 3,056
研究概览
简要总结
Among patients who treated with DES for acute coronary syndrome, the incidence of net adverse clinical event was significantly lower in those with the ticagrelor monotherapy after 3-month DAPT than those with the currently recommended ticagrelor-based 12-month DAPT, mainly driven by lower major bleeding.
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 19(Year) 至 79(Year)（—）
- 性别
- All
入选标准
- •1. Patients = 19 years old 2. Patients who received new
- •generation sirolimus-eluting (Osiro®) stent implantation for treating ACS,
- •including acute MI and unstable angina 3. Patients without significant clinical
- •events such as MI, stent thrombosis or revascularization until 3 months after
- •PCI 4. Provision of informed consent
排除标准
- •1. Age> 80 years 2. Increased risk of bleeding, anemia,
- •thrombocytopenia 3. A need for oral anticoagulation therapy 4. Pregnant women or
- •women with potential childbearing 5. Life expectancy < 1 year 6. Patients
- •receiving a potent CYP3A4 inhibitor (eg, ketoconazole, clarithromycin,
- •napjodone, ritonavir, atazanavir) 7. Patients with a history of intracranial
- •bleeding 8. Patients with moderate to severe hepatic impairment 9. Patients at
- •risk of bradykinesia (based on licensing and clinical
- •literature)
研究者
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