Impact Of Supervised 12-Week-Combined Physical Training In Heart Failure Patients: A Randomized Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 主要终点
- Questionnaire about quality of life
研究概览
简要总结
Purpose: Physical exercise exerts favorable impact on functional capacity (FC) and quality of life (QL) in patients with heart failure (HF). It is believed that the combined aerobic and resistance physical training (CPT) supervised by physical educator is better than only prescription of unsupervised exercise. The aim of this study is to compare the effects of a CPT program on the FC and QL of HF patients with reduced ejection fraction (HFREF) with the practice medical routine prescription of regular physical activity and correlate these findings with clinical and echocardiographic variables.
Methods: A longitudinal prospective study included 28 consecutive HFREF patients randomly divided in two age- and gender- matched groups: Trained Group (TG, n = 17), patients undergoing 12 weeks of supervised CPT and Non Trained Group (NTG, n = 11), patients receiving only medical prescription to practice regular physical exercise. All patients were submitted to clinical evaluation, transthoracic echocardiography, Cooper walk test and QL questionnaire before and after the study protocol. Student t test or Mann-Whitney test were performed for groups comparison and correlation tests for the same group variable associations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with heart failure with LVEF <50%;
- •Patients with optimized drug therapy;
- •Age over 18 years.
排除标准
- •Heart failure NYHA class IV and/or Stage D;
- •Decompensated HF in the last three months;
- •Atrial fibrillation and/or implantable device at the moment of inclusion;
- •Patients with chronic obstructive pulmonary disease (COPD);
- •Patients with biomechanical limitations of physical activity.
结局指标
主要结局
Questionnaire about quality of life
时间窗: up to 12 weeks of research
Cardiorespiratory evaluation (VO2 in Mets)
时间窗: up to 12 weeks of research
Morphological echocardiographic variables (mm)
时间窗: up to 12 weeks of research
Sistolic Function echocardiographic variables (Percentage)
时间窗: up to 12 weeks of research
Diastolic Function echocardiographic variables (cm/s)
时间窗: up to 12 weeks of research
次要结局
- Anthropometric measurements (cm)(up to 12 weeks of research)
- Body composition (%fat percentage)(up to 12 weeks of research)
- Presence of comorbidities(up to 12 weeks of research)
- Blood pressure measurement (mmHg)(up to 12 weeks of research)
研究者
Tainá Fabri
Master's degree
Universidade Estadual Paulista Júlio de Mesquita Filho
