Comparing the Antiplaque Efficacy of Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients-A Triple Blind Randomised Controlled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- To compare the plaque inhibitory effect of titania nanoparticle infused fluoride varnish and conventional fluoride varnish in fixed orthodontic patients.
研究概览
简要总结
In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed orthodontic patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 16 Years 至 30 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients planned for fixed orthodontic treatment.
- •Patients within age group 16-30 years.
- •Patient with no history of previous orthodontic treatment.
- •Patients with no active periodontal diseases.
排除标准
- •Patient undergoing any antibiotic therapy.
- •Patients with any craniofacial abnormality.
- •Patient with mixed dentition
研究组 & 干预措施
Group A
Group A will receive topical application of conventional fluoride varnish.
干预措施: Fluoride varnish (Procedure)
Group B
Group B will receive topical application of titania nanoparticle infused varnish.
干预措施: Novel titania nanoparticle infused fluoride varnish (Procedure)
结局指标
主要结局
To compare the plaque inhibitory effect of titania nanoparticle infused fluoride varnish and conventional fluoride varnish in fixed orthodontic patients.
时间窗: 6 months
Plaque will be assessed quantitatively by modified plaque index.
次要结局
- To measure plaque bacterial load and pH following application of titania nanoparticle infused and conventional fluoride varnish in fixed orthodontic patients.(6 months)
研究者
Afifa Fahim
Principal Investigator
Pakistan Institute of Medical Sciences