NCT03784378已完成1 期
RXDX-105 for the Treatment of Patients With Non-Small Cell Lung Cancer (NSCLC) Harboring a RET Gene Fusion and a Patient With Ovarian Cancer Harboring a BRAF Gene Mutation
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 3
- 试验地点
- 1
- 主要终点
- Evaluation during treatment/intervention
研究概览
简要总结
This study is being done to see if people with Non-Small Cell Lung Cancer (NSCLC) or ovarian cancer benefit from continued treatment with the study drug, RXDX-105.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •This individual patient protocol includes treatment for 3 patients previously enrolled on IRB #15-270 (phase1/1b clinical trial RXDX-105-01):
排除标准
- •Any patients other than those described above are excluded.
研究组 & 干预措施
Participants previously enrolled on Study of RXDX-105
Experimental
Participants were previously enrolled on Study of RXDX-105
干预措施: RXDX-105 (Drug)
结局指标
主要结局
Evaluation during treatment/intervention
时间窗: Through study completion, up to five years.
Safety assessments will be performed as standard of care and as clinically indicated. This will include monitoring of adverse events, including serious adverse events including CTCAE grading.
次要结局
未报告次要终点
研究者
研究点 (1)
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